Sep 20, 2006 (CIDRAP News) – Roche announced last week that its United States supply chain for oseltamivir (Tamiflu), used to treat avian influenza and seasonal flu patients, is fully operational, meaning all aspects of its production are based on US soil.The company said it now has the capability to produce 80 million treatment courses of the drug annually in the United States, which is stockpiling oseltamivir as part of efforts to prepare for a flu pandemic.The US Department of Health and Human Services (HHS) had asked Roche to establish a system that involves US sources for all phases of osteltamivir production, from synthesizing shikimic acid, the starting material, to packaging the medication, the company said in a news release.”The ability to produce Tamiflu from start to finish on US soil is a significant milestone that will help ensure access to Tamiflu when and where it is needed,” said George Abercrombie, president and chief executive officer for Hoffman-La Roche, Inc., the company’s US pharmaceutical division.The company said HHS has ordered 21.3 million treatment courses of oseltamivir for the Strategic National Stockpile, all of which will be delivered by the end of this year. Marc Wolfson, a spokesman for the HHS Office of Public Health Emergency Preparedness in Washington, DC, verified that information for CIDRAP News.The long-term goal for the stockpile is 81 million courses by the end of 2008, according to Wolfson and Roche. Of that total, HHS says it will buy 50 million courses and will provide a 25% subsidy for states to purchase another 31 million courses.Roche says that with its own manufacturing network and 16 external contractors, it has more than enough capacity to meet the osteltamivir orders from 75 countries that are stockpiling the drug. Global annual production capacity will reach 400 million treatment courses by the end of this year, the company said.Approved for prevention and treatment of influenza in adults and children 1 year and older, osteltamivir is intended to treat influenza viruses in all clinical settings. It has been shown to be active against the H5N1 virus in the laboratory and in animals that are infected with an H5N1 avian flu strain taken from humans, according to Roche.See also:Sep 14 Roche press releasehttp://www.roche.com/med-cor-2006-09-14
A year ago, I had the honor of being a small part of the dice when launching an online travel portal – The Plitvice Times.In a conversation with one of the initiators of the portal Ante Fumić a year ago, before launching the project, it was clear that he and the entire team from the project has a clear goal and desire – to promote Lika and its surroundings through tourism to as many visitors from Croatia, especially abroad learned about the amazing tourist stories provided by Lika. A great idea and project was my reaction and advice that the portal has great growth potential, especially because it is about foreigners as a target group of readers, and is not dependent on the Croatian market. “Plitvice and Lika definitely need such a portal. Go and try, you have nothing to lose. Go ahead bravely “One hundred questions in my head, as with any new business venture, but most importantly the whole team had the courage, believed in the project, passion and ultimately a clear vision. But the most important thing is that they have started, how many projects fail because they are waiting for the “right” moment and do not even take the first step, because it is one idea and quite another to implement the idea on the market. “We’ve been working on the project for over half a year and now the magazine is finally out. It is constantly said that Plitvice, and especially the whole of Lika, are not active enough in promotion on foreign markets, so an entrepreneurial initiative was born and we have now turned the idea into reality as the only English media in the area that exclusively targets foreign markets.”Said Ante Fumić, when launching the portal a year ago.Day by day, The Plitvice Times project positioned itself excellently on the media scene, knocking out the first perfume as an authentic and unique souvenir. Yes, a perfume, and not just any perfume, but a premium perfume based on orchids, moss and plums that grow in the Plitvice area. The goal is to reach a million visits, we are waiting for that goal to be fulfilled. Step by step, day by day, the Plitvice Times portal will be, in fact already, the first place for all tourist information about Plitvice, Lika and the surrounding area in English.Today, the whole project has gone a step further, and the first printed edition has been presented travel magazine The Plitvice Times.The tourist magazine is the only one of its kind in the wider area of Plitvice and its goal is to interest many tourists who visit the wider area of Plitvice every day with the interesting content of the surrounding destinations. “The Plitvice Times, is the first and only tourist magazine that covers this area, and is intended primarily for many foreign tourists who come here, but also for all potential visitors who are just planning their trip, because it will come to life on the online platform. The goal is to present to the readers all the beauties and experiences of this area and to interest them to stay longer in Plitvice.”Point out the editorial board of the tourist magazine The Plitvice Times.The first printed edition brings fresh information, many interesting stories, beautiful photos and personal experiences, so you can read articles about the abandoned air base Željava, the castle in Ozalj, an active vacation at the foot of Plješivica, an emotional story from Rastoke, but also little-known facts about orchids and a perfume created in honor of that valuable plant. ”“Humans of Plitvice ”is a category in which tourists who enjoy their touring experiences are prominent, and local people from the Plitvice area are not forgotten, so this time you will find the story of Tamara, a travel blogger who travels to the world from Plitvice. You can also find out the connection between the planetarily popular Oprah Winfrey and Plitvice, as well as why Italian Vogue chose this place for its special photoshoot. “They conclude in their statement.Otherwise, the magazine will be published according to the seasons, and the next issue is expected in January 2019. Of course, it is important to emphasize that the portal and the magazine are exclusively in English, and it is planned to start with other languages, especially Chinese.We need such entrepreneurs and ambassadors of Croatian tourismBut to get back to the beginning of the story again, the team behind the whole project bravely set off, they didn’t wait for the right moment because it’s never there, the right moment is always now. They set out to test the idea in the market and see how the whole project would develop. And that is a very important entrepreneurial message. Just get going, even though the project fails, you tried, you did your best, but you didn’t sit in the safety of your couch and whine on Facebook. Trust me, if the project ends ingloriously, you will learn a lot, mostly so far and meet some new people as well as open some new doors.And again, going to the print edition of a magazine in Croatia is crazy for most, both because of the high production costs and the chaos on the media scene, not to mention future potential sponsors to make the whole project financially worthwhile.Be like the team from The Plitvice Times. The right moment is now. Go and set clear goals, not desires. It’s one thing to want something, it’s another when you set clear goals for yourself.What is your new travel story?Related news:“THE PLITVICE TIMES” – THE FIRST TOURIST MAGAZINE IN ENGLISH LANGUAGE PROMOTING STORIES FROM ALL OVER THE CHARACTERPLITVICE GOT ITS PREMIUM PERFUME AS A TOURIST AUTHENTIC SOUVENIR
The Black Stars Brazil 2014 budget has been chanced upon by our sources and it reveals the details of the budget for the mundial which begins in June.Participation fee $1.7mQualification bonus preliminary stages $1.8mQualification bonus 1/16 stage $837,000Quarter finals $1mSemi finals $1.2m Third-place $1.4mFinals $1.6mDETAILS…Boarding and lodging of other officials: $750/Day for 35 days = $131,000Laundry $30,000 Per diem/Allowance for 33 (Players and technical team) $115,00022 other officials $150/Day for 35 days $115,000Medicals $50,000Protocol $150,000Foodstuff $10,000 Complimentary ticket for players and technical handlers @1/16 Stage = $18,000Accountable Impress for 4 scouts for travels, accommodation/meals – $30,000 each = $120,000Honoraria for 4: Media Officer, Protocol Officer, Extra Doctor, Extra Physiotherapist $12,632 each*4= $50,528Honoraria for team: two National Security Officers, two caterers and drummer @ $5,263 each = $26,315Honoraria for 4 scouts and 1 therapist @ $10,526 each = $ 52,630 Honoraria for two backroom staff $12,632Bonuses -$15,789 per player at preliminary stageHead coach $31,578Bonus for 7 management team members (Prelims) = A bonus of a player for three matches ( 7 X $15,782 X THREE) = $331,000Bonus for 7 management members at 1/16 Stage (7 X $21,000) = $147,000 Bonus for 7 management members @ quarter final stage $184,000Bonus for 7 management members @ semi finals stage $221,000Bonus for 7 management members @ finals $257,000Bonus for 23 players 2 assistant coaches, 1 physio, 1 psychologist $15,000/each @ preliminary stagePlayer bonus @ 1/16 stage- $484,000 for 23 ($21,000/player) Player bonus @ quarter final stage – $26,000/player (X 23) = $598,000Bonus for head coach @ quarter final stage $52,000Bonus for match analyst, welfare, masseur, kits manager $18,000 each @ 1/16 stage – $72,000NB: According to the spokesperson, GFA does not know the details of the approved budget so can’t speak on the figures.Just hoping probably after the World Cup, the ‘state secret’ as termed by the GFA Spokesman will tell us otherwise when the account is being rendered.